Trattamento delle lesioni ossee traumatiche con le BMPs: revisione della letteratura
Abstract
TREATMENT OF TRAUMATIC BONE INJURIES WITH BMPS: A REVIEW OF THE LITERATURE
The treatment of open fractures and fracture non-unions is a challenging situation for the orthopaedic surgeon. The
use of bone morphogenetic proteins (BMPs) in the treatment of these injuries has been assessed by several authors.
Indicated for the treatment of open tibial fractures treated with intramedullary fixation and for the treatment of
tibial long-bone non-union, BMPs nowadays have been tested in other anatomical sites. Although the clinical efficacy
in these cases has not been demonstrated definitely, the use of BMPs has also been considered on the basis of its high
cost. This review summarises the evidence present in the literature on BMPs for the treatment of open fractures and
non-unions.
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright
© Società Italiana Ortopedici Traumatologi Ospedalieri d’Italia 2019 , 2019
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